5G and Beyond Networks become increasingly complex and heterogeneous, with diversified and high requirements from a wide variety of emerging applications. The complexity and diversity of Telecom networks place an increasing strain on maintenance and operation efforts. Moreover, the strict security and privacy requirements present a challenge for mobile operators to leverage network data. To detect network faults, and mitigate future failures, prior work focused on leveraging traditional ML/DL methods to locate anomalies in networks. The current approaches, although powerful, do not consider the intertwined nature of embedded and software-intensive Radio Access Network systems. In this paper, we propose a Bi-level Federated Graph Neural Network anomaly detection and diagnosis model that is able to detect anomalies in Telecom networks in a privacy-preserving manner, while minimizing communication costs. Our method revolves around conceptualizing Telecom data as a bi-level temporal Graph Neural Networks. The first graph captures the interactions between different RAN nodes that are exposed to different deployment scenarios in the network, while each individual Radio Access Network node is further elaborated into its software (SW) execution graph. Additionally, we use Federated Learning to address privacy and security limitations. Furthermore, we study the performance of anomaly detection model under three settings: (1) Centralized (2) Federated Learning and (3) Personalized Federated Learning using real-world data from an operational network. Our comprehensive experiments showed that Personalized Federated Temporal Graph Neural Networks method outperforms the most commonly used techniques for Anomaly Detection.

Screening is critical for prevention and early detection of cervical cancer but it is time-consuming and laborious. Supervised deep convolutional neural networks have been developed to automate pap smear screening and the results are promising. However, the interest in using only normal samples to train deep neural networks has increased owing to class imbalance problems and high-labeling costs that are both prevalent in healthcare. In this study, we introduce a method to learn explainable deep cervical cell representations for pap smear cytology images based on one class classification using variational autoencoders. Findings demonstrate that a score can be calculated for cell abnormality without training models with abnormal samples and localize abnormality to interpret our results with a novel metric based on absolute difference in cross entropy in agglomerative clustering. The best model that discriminates squamous cell carcinoma (SCC) from normals gives 0.908 +- 0.003 area under operating characteristic curve (AUC) and one that discriminates high-grade epithelial lesion (HSIL) 0.920 +- 0.002 AUC. Compared to other clustering methods, our method enhances the V-measure and yields higher homogeneity scores, which more effectively isolate different abnormality regions, aiding in the interpretation of our results. Evaluation using in-house and additional open dataset show that our model can discriminate abnormality without the need of additional training of deep models.

Introduction: Urine cytology plays an important role in diagnosing urothelial carcinoma (UC). However, urine cytology interpretation is subjective and difficult. Morphogo (ALAB, Boston, MA, USA), equipped with automatic acquisition and scanning, optical focusing, and automatic classification with convolutional neural network has been developed for bone marrow aspirate smear analysis of hematopoietic diseases. The goal of this preliminary study was to determine the feasibility of developing a machine learning algorithm on Morphogo for identifying abnormal urothelial cells in urine cytology slides. Methods: Thirty-seven achieved abnormal urine cytology slides from cases with the diagnosis of atypical urothelial cells and above (suspicions or positive for UC) were obtained from 1 hospital.

Liquid-based cytology (LBC) is a reliable automated technique for the screening of Papanicolaou (Pap) smear data. It is an effective technique for collecting a majority of the cervical cells and aiding cytopathologists in locating abnormal cells. Most methods published in the research literature rely on accurate cell segmentation as a prior, which remains challenging due to a variety of factors, e.g., stain consistency, presence of clustered cells, etc. We propose a method for automatic classification of cervical slide images through generation of labeled cervical patch data and extracting deep hierarchical features by fine-tuning convolution neural networks, as well as a novel graph-based cell detection approach for cellular level evaluation. The results show that the proposed pipeline can classify images of both single cell and overlapping cells. The VGG-19 model is found to be the best at classifying the cervical cytology patch data with 95 % accuracy under precision-recall curve.

Papnet is a commercial neural network-based computer program for assisted screening of Pap (cervical) smears. A Pap smear test examines cells taken from the uterine cervix for signs of precancerous and cancerous changes. A properly taken and analysed Pap smear can detect very early precancerous changes. These precancerous cells can then be eliminated, usually in a relatively simple office or outpatient procedure. Detected early, cervical cancer has an almost 100% chance of cure. Traditionally, Pap smear testing relies on the human eye to look for abnormal cells under a microscope.